July Image of the Month

Image of the Month

Thy-1 YFP positive neurons and axons in the mouse cortex or spinal cord. Projection image of either 1mm or 2mm thick “CLARITY” tissue. Images taken with Leica SP5.

Image by Rory Spence from the laboratory of Allan MacKenzie-Graham.

 

Bai image

Neuroscience News Featured Article

BRI PHYSIOLOGISTS CHALLENGE TRADITIONAL NEUROSCIENCE IN THE PAST AND PRESENT

Image: Homology model of a P2X channel, with the pore lining second transmembrane domain shown in
grey, courtesy of the Khakh laboratory. More about Dr. Khakh here.
 

Varghese John

Introducing the BRI's New Member

VARGHESE JOHN, PhD

The BRI welcomes new member Varghese John, PhD. John, an associate adjunct professor of neurology and principal investigator in the department’s new Drug Discovery and Translational Laboratory. He is also co-director of the Alzehimer’s Drug Development Network. John is an accomplished medical chemist who develops new therapeutics for neurodegenerative disorders with a focus on Alzheimer’s disease, Parkinson’s disease, and amyotrophic lateral sclerosis. Other research interests include development of new treatment approaches for traumatic brain injury, and glioblastoma multiforme. John joins UCLA from the Buck Institute for Research and Aging.

Image: John (second from left) and his drug discovery team (l to r): Jesus Campagna Barbara Jagodzinska, and Patricia Spilman.

Varghese John

In the News

NEW BLOOD TEST PROVIDES MAJOR BREAKTHROUGH IN DIAGNOSIS OF ALZHEIMER'S DISEASE

Dr. Liana Apostolova, BRI member and director of the neuroimaging laboratory at the Mary Easton Center for Alzheimer’s Disease Research at UCLA leads a study that provides the first evidence that a simple blood test could be developed to confirm the presence of beta amyloid proteins in the brain – a hallmark of Alzheimer’s disease. The blood test would be safe, affordable and easy to administer in large groups or in rural areas. More here.

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The Interdepartmental Program for Neuroscience 

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Upcoming Events

JOINT SEMINARS IN NEUROSCIENCE WILL COMMENCE
TUESDAY, SEPTEMBER 29th, 2015

Speaker: Loren Looger, PhD, Howard Hughes Medical Institute, Janelia Research Campus, Ashburn, Virginia
Host: Baljit Khakh, PhD, Professor, Neurobiology and Physiology, David Geffen School of Medicine, Associate Director for Research, Brain Research Institute, UCLA
Title: To be announced

Dr. Looger uses protein engineering to create tools -- including neurotransmitter detectors, improved labels for in vivo imaging, designed receptors, and rewired neural circuits -- to study the brain. His lab combines computational and evolutionary methods to create new reagents to characterize and manipulate the assembly and function of neural circuits. 

5:00pm. Neuroscience Research Building Auditorium, UCLA

 

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