Genome Editing

Mission and Goals:

Rapid advancements in genome editing technology such as the CRISPR/Cas9 system have revolutionized the way to make transgenic knockout/knock-in mice in brain research.  With such technology, it is feasible to generate the mutant mice with targeted genetic mutations within 2-3 months to study gene function or model human disease in neural stem cells and pluripotent stem cells.  To promote the application of the CRISPR technology in ncuroscience research, we propose to initiate this new Affinity Group in the format of group meetings and workshops.

 

How to Join:

Guoping Fan, PhD  (Leader)
Professor, Human Genetics
Gonda Research Building
695 Charles Young Dr., S
Mail Code:  708822
Phone:310-267-0439;  FAX:  310-794-5446
Email:  gfan@mednet.ucla.edu
Web:  http://labs.genetics.ucla.edu/fan/

 

William Yang, MD, PhD  (Co-Leader)
Professor, Psychiatry and Biobehavioral Sciences
Gonda Research Building
695 Charles Young Dr., S
Mail Code:  176122
Phone:  310-267-2761
Email:  xwyang@mednet.ucla.edu
Web:  http://yanglab.npih.ucla.edu/