Mark A. Frye, Ph.D.


Director, Molecular, Cellular & Integrative Physiology GPB Home Area

Professor, Integrative Biology and Physiology


Member, Brain Research Institute

Neuroscience GPB Home Area

Contact Information

Office Phone Number: (310) 825-5360

Laboratory Address:

Terasaki Life Science



Dr. Frye began his research career at Union College, then received his PhD at the University of Washington. As a postdoctoral fellow at Berkeley and then at Caltech, he began to work on multi-sensory processing and motor control of flight in fruit flies. He is currently a member of the Department of Physiological Science, and teaches courses in integrative and comparative animal physiology. He is the reciepient of a Sloan Foundation Fellowship, and his laboratory examines sensory fuison and sensory-motor integration for the control of walking and flight in fruit flies.


Theobald, JC Frye, MA   Animal Behavior: flying back-to-front, Curr. Biol. , 2008; 18(4): r169.
Chow DM Frye MA   Context dependent olfactory enhanced optomotor flight control in Drosophila, J. Exp. Biol. , 2008; 211: 2478-2485.
Duistermars, BJ Frye, MA   Cross-modal visual input for odor tracking during fly flight, Curr. Biol. , 2008; 18(4): 270-275.
Theobald JC Duistermars BJ Ringach DL Frye MA   Flies see second order motion, Curr. Biol. , 2008; 18(11): r464.
Duistermars, B.J. Reiser, M.B. Zhu, Y. Frye, M.A.   Dynamic properties of large-field and small-field optomotor flight responses in Drosophila, Journal of Comparative Physiology A, 2007; in press: .
Reynolds, A. Frye, M.A.   Free-flight odor tracking in Drosophila is consistent with a mathematically optimal intermittent scale-free search, PLoS ONE, 2007; 2(4): 354.
Frye, MA   The neuromechanics of fly flight control, Invertebrate Neurobiology, 2007; 209-229.
Duistermars, BJ Chow, D Condro, M Frye, MA   The spatial, temporal, and contrast properties of expansion and rotation flight optomotor responses in Drosophila, J. Exp. Biol. , 2007; 210: 3218-3227.
Frye, MA Dickinson, MH   Visual edge orientation shapes free-flight behavior in Drosophila, Fly, 2007; 3: 153-154.
Humbert, J.S. Frye, M.A.   Extracting behaviorally relevant retinal image motion cues via wide-field integration, Proc. IEEE American Controls Conference, 2006; 2724-2729.
Frye, MA Dickinson, MH   Closing the loop between neurobiology and flight behavior in Drosophila Current opinion in neurobiology. , 2004; 14(6): 729-36.
Frye, MA Dickinson, MH   Fly flight: a model for the neural control of complex behavior Neuron. , 2001; 32(3): 385-8.