Neuroscience News Winter 2009


ARCHIVED EDITION
Published by the UCLA Brain Research Institute
Winter, 2009
Volume 18, No. 1

In this issue:

· BRI Welcomes a New Member- Dr. Sophie Sokolow
· Congratulations to Dr. Michael Phelps and Dr. X. William Yang
· Mark Your Calendars (http://www.bri.ucla.edu/bri_calendar)
· BRI Brain Awareness Week- March 9-13, 2009(http://www.bri.ucla.edu/bri_education/scienceoutreach.asp)
· Fellowships, Awards & Grants – Opportunities & UCLA T32 neuroscience training grants
· Core Facilities/Resources – Carol Moss Spivak Confocal Imaging Core moved to the CNSI
· Employment – Opportunities/Candidates

    THE BRI WELCOMES A NEW MEMBER

    The Brain Research Institute welcomes its newest member, Dr. Sophie Sokolow, Assistant Professor in the School of Nursing at UCLA.

    Sophie Sokolow received her pharmacy degree from the Free University of Brussels, Belgium in 1994. From 1994 to 2004, Dr Sokolow worked as a community pharmacist and was also a consultant to the Belgian Ministry of Public Health where she provided drug monitoring and reporting services. In 2004, Dr. Sokolow received her Ph.D. in biomedical sciences from the Free University of Brussels, Belgium. Her Ph.D. thesis was completed in the laboratories of André Herchuelz (Department of Pharmacotherapeutics) and Stéphane Schurmans (Institute of Interdisciplinary Research in Human Biology). Her graduate work included the production of a new mouse models for the sodium-calcium exchangers 3 (Ncx3-/-) which allowed her to investigate NCX3 implication in the neuromuscular function. After completion of her Ph.D. thesis, Dr Sokolow joined UCLA’s Duchenne Muscular Dystrophy Research Center as a postdoctoral fellow in the laboratory of Dr. James Tidball in the Department of Physiological Science where she studied the cellular immune response in muscular dystrophy. In 2007, Dr Sokolow pursued a second postdoctoral appointment in the laboratory of Dr. Karen Gylys in the UCLA School of Nursing where she investigated the molecular mechanisms involved in synaptic loss occurring in Alzheimer’s disease. In 2008, Dr Sokolow was appointed Assistant Professor in the UCLA School of Nursing where she is currently teaching Advanced Pharmacology. In 2008, Dr Sokolow earned the FPGEC (Foreign Pharmacy Equivalency Examination Certificate) from the American Association Board of Pharmacy.

    Dr. Sokolow’s research explores the molecular mechanisms involved in cellular calcium homeostasis dysregulation occurring in neurodegeneration, with a particular focus on Alzheimer’s disease. “The Sokolow laboratory focuses on understanding the molecular mechanisms involved in the pathogenesis of neurodegenerative disorders. This includes Alzheimer’s disease (AD), ischemia and essential tremor. The laboratory has special expertise in AD and calcium signaling. Our group investigates the calcium hypothesis in synaptic amyloid-beta protein (Abeta) buildup and tau phosphorylation. Abeta and p-tau are the major AD pathological characteristics. 

    Using post-mortem human brain regions affected by Abeta and different mouse models of AD, we are studying specific proteins involved in the calciumopathy of AD pathology in order to identify key players that could yield insights into new AD therapies.”

    The Brain Research Institute is happy to welcome its newest member.

    CONGRATULATIONS!

    The BRI congratulates the meritorious achievements of Dr. Michael Phelps and Dr. X. William Yang.

    Dr. Michael Phelps is one of the two UCLA scientists awarded more than $1.8 million in state grants to develop innovative tools and technologies that will help overcome technical hurdles in advancing basic, translational and clinical stem cell research. Dr. Michael Phelps, Chairman and Norton Simon Professor of Molecular and Medical Pharmacology, will receive a two-year, $914,096 grant to develop ways to follow the fate and function of transplanted stem cells in patients using positron emission tomography, a technology developed by Phelps.

    Dr. X. William Yang is the recipient of a McKnight Endowment Fund for Neuroscience Award. The McKnight Endowment Fund for Neuroscience awarded six grants totaling $1.8 million to research projects exploring the biology of neurological and psychiatric diseases. The awards are given annually to support research by U.S. scientists working on better methods to diagnose, prevent and treat injuries or diseases of the brain or spinal cord. The awards encourage novel, cross-disciplinary approaches to brain research and are designed to extend the knowledge achieved through basic research to clinical practice.

    X. William Yang, M.D., Ph.D., Associate Professor, Psychiatry and Biobehavioral Sciences received an award for his research on “Basal Ganglia Circuitry and Molecular Deficits in a Mouse Model of Tourette Syndrome.” Tourette syndrome (TS) is a relatively common childhood-onset neuropsychiatric disorder characterized by multiple motor and vocal tics. Many TS patients also have other neurobehavioral conditions, such as obsessive compulsive disorder and attention deficit hyperactivity disorder. Although TS is thought to have a strong genetic component, the disease-causing mutant genes have not yet been elucidated. Neuropharmacological and imaging studies implicate basal ganglia dysfunction in TS, but how basal ganglia molecular and circuitry dysfunction may cause the behavioral deficits characteristic of TS and related conditions remains unclear. Dr. Yang uses mouse genetic approaches to test the hypothesis that developmental and/or functional imbalance of the two major basal ganglia neural circuits, the direct and indirect pathways, may underlie the behavioral manifestations of TS.

    Warm congratulations to Dr. Phelps and Dr. Yang from the staff, students and faculty of the Brain Research Institute!

    MARK YOUR CALENDARS

    JOINT SEMINARS IN NEUROSCIENCE

    The Joint Seminars in Neuroscience series will resume Winter quarter beginning January 6, 2009. Please mark your calendars and plan to join us every Tuesday at 4:00 p.m. in the Neuroscience Research Building Auditorium.

    The Joint Seminars in Neuroscience are sponsored by the Brain Research Institute, the Semel Institute for Neuroscience & Human Behavior, and the David Geffen School of Medicine at UCLA.

    Joint Seminars in Neuroscience 
    Spring Quarter 2009

    March 31, 2009 
    Charles (Tom) Sawyer Distinguished Lecture 
    S. Marc Breedlove, Ph.D., Barnett Rosenberg Professor of Neuroscience, Michigan State University, East Lansing 
    “The Role of Androgens in Behavior” 
    (Host: Art Arnold, the LNE; arnold@ucla.edu)

    April 7, 2009
    Jane R. Taylor, Ph.D., Charles B.G. Murphy Associate Professor of Psychiatry, Yale University School of Medicine, New Haven, Connecticut
    “Title to be Determined”
    (Host: David Jentsch; jentsch@psych.ucla.edu)
    April 14, 2009
    Patricia S. Churchland, Ph.D., Department of Physiology, University of California, San Diego; Salk Institute, San Diego
    “Morality & The Social Brain” 
    (Host: Dean Buonomano; dbuono@ucla.edu)

    April 21, 2009
    Joshua Corbin, Ph.D., Center for Neuroscience Research, Department of Pediatrics and Pharmacology, George Washington University School of Medicine; Children's Research Institute, Children's National Medical Center, Washington, D.C.
    “Generation of Neuronal Cell Diversity in the Developing Mammalian Brain”
    (Host: Seema Tiwari-Woodruff; seemaw@ucla.edu)

    April 28, 2009
    Nirao M. Shah, M.D., Ph.D., Biomedical Department of Anatomy, University of California, San Francisco
    “Sex, Genes, and Videotape: Representation of Gender in the Brain” 
    (Host: Stephanie White; sawhite@ucla.edu)

    May 5, 2009
    Arturo Alvarez-Buylla, Ph.D., Professor of Neurological Surgery, Heather and Melanie Muss Endowed Chair, Principal Investigator, Brain Tumor Research Center, University of California, San Francisco
    “Title to be Determined”
    (Host: James Waschek; jwaschek@mednet.ucla.edu)

    May 12, 2009
    Chi-Hon Lee, M.D., Ph.D., Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland
    “Dissecting the Peripheral Chromatic Circuit of the Drosophila Visual System”
    (Host: Larry Zipursky; lzipursky@mednet.ucla.edu

    May 19, 2009
    The 17th Annual Samuel Eiduson Student Lecture
    Doris Payer, Interdepartmental Ph.D. Program for Neuroscience, University of California, Los Angeles
    “Title to be Determined”
    (Host: Michael Levine; mlevine@mednet.ucla.edu)

    May 26, 2009
    David P. Corey, Ph.D., Department of Neurobiology, Harvard Medical School, Boston, Massachusetts
    “Macro- and Micromechanics of Hearing” (Host: Peter Narins; pnarins@ucla.edu)

    June 2, 2009
    Michael P. Kilgard, Ph.D., Cognition and Neuroscience Program, School of Behavioral and Brain Sciences, University of Texas at Dallas
    “Neural Coding and Plasticity in the Auditory System: From Tones to Speech”
    (Host: Dean Buonomano; dbuono@ucla.edu)


    2009 Brain Awareness Week at the Brain Research Institute

    The BRI sponsors multiple scientific and educational outreach programs throughout the year for the greater Los Angeles community. Events include school visits, tours and demonstrations, and the largest single event of the year, Brain Awareness Week.

    During a typical BAW, students from schools in Los Angeles county visit the BRI on a very special field trip to celebrate the brain. Each day K-12 students arrive in front of the Gonda (Goldschmied) Neuroscience and Genetics Research Center to join Project Brainstorm leaders, Nanthia Suthana, Marina Ziehn and Angela Rizk-Jackson. The tour begins with a brief overview on the structure and function of the brain, and then graduate students conduct presentations on the brain, including some hands-on activities, and educational, age-appropriate presentations ranging from brain injury, two-point discrimination testing, sensation, synaptic function, hemispheric differences, motor system and lobe functions set up by the Interaxon undergraduate group. The students then visit research laboratories in the Gonda Center where they hear presentations about research on topics such asAplysiaDrosophila, and memory research. Regardless of grade level, all students express great curiosity, insight, and interest throughout the entire day while being guided through the fascinating neuroscience research environment at UCLA.

    This year, Project Brainstorm team leader, Nanthia Suthana was able to secure funding through several grant submissions. The ACNP grant was written in collaboration with Drs. Edythe London, Martin Iguchi and Chris Evans. So this year will be the largest BAW ever-- we will be bringing 500 students from low-income Title 1 Los Angeles schools to BAW! Students will visit the UCLA campus and the BRI March 9-13, 2009. The full-day events include Neuroscience educational activities (real human brain demos, interactive activities, and lab tours), UCLA campus tours, and Science Diversity Career panels. Funding for transportation, lunch, and expenses is provided by the American College of Neuropsychopharmocology (ACNP), Society for Neuroscience (SfN), UCLA Brain Research Institute (BRI), and the UCLA Campus Program's Fund. This event is hosted by the UCLA BRI and the Advanced Microscopy/Spectroscopy Shared Facility at the California NanoSystems Institute. This event is made possible through our dedicated volunteers: graduate students, undergraduate students, and faculty from the Neuroscience Interdepartmental Ph.D. Program, student groups Project Brainstorm, STEM-PLEDGE (Science, Technology, Engineering, Mathematics - Promoting Diversity and Enhancing Leadership in Graduate Education), Interaxon, SIGN (Student Interest Group in Neurology), and NUS (Neuroscience Undergraduate Society)! For more information, please visit http://www.studentgroups.ucla.edu/projectbrainstorm/index.htmland/or email us: brainstorm@ucla.edu.

    FELLOWSHIPS, AWARDS & GRANTS

    2010 McKnight Brain Disorders Awards

    he McKnight Endowment Fund for Neuroscience supports innovative research designed to bring science closer to the day when diseases of the brain can be accurately diagnosed, prevented, and treated. To this end, the McKnight Neuroscience of Brain Disorders Award assists scientists working to apply the knowledge achieved through basic research to human brain disorders, particularly those that affect memory.
    Use of Award Funds:

    The McKnight Endowment Fund for Neuroscience is particularly interested in proposals that address memory under normal and pathological conditions. This includes proposals that address mechanisms of memory at the synaptic or cellular level, as well as proposals at the cognitive or behavior level in animals, including humans. Proposals will also be considered that permit fundamentally new approaches and accomplishments toward the development of translational research in the neurosciences related to memory.

    Projects restricted to the creation of conventional mouse knockouts in candidate disease genes identified by association studies, or to broadly overexpress those genes, are discouraged. In addition, projects to perform genetic interaction screens on disease genes in model organisms (yeast, worm, fly, fish) will not be considered, unless the project includes substantive specific aims that investigate the disease relevance of any new genes so discovered in human or mammalian model systems.

    Eligibility:
    Candidates should be a scientist doing basic biological or biomedical research who proposes to apply his/her knowledge and experience to improve the understanding of a brain disorder or disease. Collaborative and cross-disciplinary applications are explicitly invited.

    Investigators who are United States citizens or lawful permanent residents conducting research at institutions within the United States are invited to apply. Applicants must be in tenured or tenured-track, faculty positions. Full professors at U.S.-based medical schools are eligible. Applicants may not be employees of the Howard Hughes Medical Institute or scientists within the intramural program of the National Institutes of Health. Applicants may not hold another McKnight for Neuroscience Award that would overlap with the Brain Disorder Award.

    Funds may be used toward a variety of research activities, but not the recipient’s salary. The PI's total laboratory funding (including PI and co-PI of all external grants) should be less than $700,000 in annual direct costs. The candidate’s other sources of funding will be considered when selecting awards.
    Selection Process:

    For an application form, please visit the website at www.mcknight.org/neuroscience, or email or call the office of The McKnight Endowment Fund for Neuroscience (info@mcknight.org; 612-333-4220). The deadline for submission is April 1, 2009. In mid-June, the selection committee will invite a small number of applicants to submit more detailed proposals, which will be due September 10, 2009. Funding begins February 1, 2010.
    Please email one PDF file of the application, including a 2-page project description, to neuro@mcknight.org. If you do not receive email confirmation of receipt of your LOI within a week of submission, please contact Eileen Maler at emaler@mcknight.org.

    The Endowment Fund has had to make some difficult decisions due to the current financial crisis. For that reason, in 2010, we can fund only up to four awards, each providing $100,000 per year for three years.


    The Whitehall Foundation -- Grants for Research in Neurobiology
    The Whitehall Foundation is accepting applications throughout the year for grants to support basic research in neurobiology, especially on how the brain's sensory, motor, and other complex functions relate to behavior. 
    Candidates eligible for these grants include tenured or tenure-track professors at accredited American institutions.

    Deadlines for letters of intent to apply are due by January 15, April 15, and October 1; the three deadlines for applications during the year are June 1, September 1, and February 15.

    The total amount and number of awards is not specified, however, the amount of individual awards range from $30,000 to $75,000 each year for up to three years. View the full announcement: http://www.whitehall.org/grants.


    The Training Program in Neural Repair
    Two postdoctoral positions are available immediately on an NIH-funded training grant for research relevant to Neural Repair at UCLA. Applicants MUST be a U.S. citizen or permanent resident of the U.S. at the time of the application. Starting date MUST be before June 30, 2009. Preference will be given to applicants who have obtained a M.D. or Ph.D. degree less than 24 months before the starting date. Appointment is for one year only. To apply, send a letter of nomination from the faculty mentor, a brief description (1-2 pages) of the research program, your graduate G.P.A., an NIH biosketch with list of publications, and two letters of recommendation to Dr. Chesselet at: mfcb114@ucla.edu. Applications will be reviewed by the TPNR steering committee as they are received and will be considered until the positions are filled. For inquiries, please contact:

    Marie-Francoise Chesselet, MD, PhD
    Program Director
    Departments of Neurology and Neurobiology David Geffen School of Medicine at UCLA
    B114 RNRC
    710 Westwood Plaza
    Los Angeles, CA 90095
    Email: mchessel@ucla.edu.


    T32/T90 Neuroscience Training Grants at UCLA

    A number of training grants offer support to neuroscience graduate students and postdoctoral fellows. Appointments are generally made each year at the beginning of the project period, but can be made during the entire year. All inquiries and applications must be submitted by the faculty mentor. The BRI frequently sends out “Call for Nominations,” so please watch for announcements. Mike Levine is submitting a T32 program to fund 1st and 2nd year Neuroscience students across the IDP, Neurobiology and Psychology programs which if successful will increase cross-talk among our training programs. 

    Of note is that the BRI has recently instated a committee (The BRI Committee for Enhancement of Neuroscience Training Programs) to determine where the BRI can help in the operation and submission of NIH T32 grants. The Chair of the Committee is the BRI Associate Director for Research Dr Bernard Balleine and several new initiatives regarding program recruitment, faculty information databases and ethics training will be put in place during the coming months.

    T32/T90 Neuroscience Training Grants at UCLA

    Grant Number

    PI Name

    Project Title

    Number Pre/Post

    Appoint.
    Period

    5T32HD007228

    Arnold, Arthur

    Neuroendocrinology, Sex Differences, and Reproduction

    5 Pre
    2 Post

    5/1-4/30

    5T32NS007449

    Chesselet, Marie-Francoise

    Training Program in Neural Repair     

    2 Pre
    2 Post

    7/1-6/30

    5T90DA022768

    Cohen, Mark

    Comprehensive Training in Neuroimaging Fundamentals and Applications   

    5 Pre

    9/30-7/31

    5T32HD007032

    De Vellis, Jean

    Mental Retardation and Developmental Disabilities

    3 Pre
    5 Post

    5/1-4/30

    5T32HD007549

    Devaskar, Sherin

    Training in Neonatal and Developmental Diseases

    7 Post

    5/1-4/30

    5T32MH015750

    Dunkel Schetter, Christine

    Biobehavioral Issues in Physical and Mental Health

    3 Pre
    2 Post

    7/1 or 9/1

    5T32MH015795

    Fanselow, Michael

    Training in Behavioral Neuroscience  

    3 Pre
    2 Post

    7/1-6/30

    1T32NS058280

    Feldman, Jack

    Training Program in Neural Microcircuits

    2 Pre
    2 Post

    1/1-12/31

    5T32NS048004

    Freimer, Nelson

    Training Grant in Neurobehavioral Genetics          

    4 Post

    7/1-6/30

    5T32MH073526

    Geschwind, Daniel

    Training Grant in Neurobehavioral Genetics

    4 Pre

    6/1-5/31

    2T32MH019384

    Glanzman, David

    Training Program in Molecular and Cellular Neurobiology

    4 Pre

    10/1-9/30; 
    7/1-6/30 in 09

    2T32MH019535

    Hinkin, Charles

    Neuropsychology AIDS Fellowship

    3 Post

    Start 7/1 thru 9/1

    5T32MH019925

    Irwin, Michael

    Post-Graduate Training Program in Psychoneuroimmunology and Mental Disorders

    3 Post
    2 yrs

    7/1-6/30

    5T32MH017140

    Leuchter, Andrew

    Research Training: Psychobiological Sciences

    5 Post

    7/1-6/30

    1T32DA024635

    London, Edythe

    Training Program in Translational Neuroscience of Drug Abuse

    3 Pre

    4/1-3/31

    5T32GM067555

    Monbouquette, Harold

    Biotechnology Training in Biomedical Sciences

    5 Pre

    7/1-6/30

    5T32NS007101

    O'Dell, Thomas

    Cellular Neurobiology

    4 Post

    7/1-6/30

    2T32DA007272

    Rawson, Richard

    UCLA Drug Abuse Research Training Center

    2 Pre
    3 Post

    1 yr--Varies

    5T32GM065823

    Tidball, James

    Training in Molecular, Cellular & Integrative Physiology

    4 Pre

    Oct 1
    1 year appt

    5T32EY007026

    Travis, Gabriel

    Vision Research Training Grant

    6 Pre
    2 Post

    Varies

    CORE FACILITIES, RESOURCES AND SERVICES

    Bioscience Cores at UCLA (http://www.bioscience.ucla.edu)

    BRI Cores:
    Carol Moss Spivak Cell Imaging Facility*
    Confocal Microscopy
    For information, contact: 
    Dr. Matt Schibler X59783 (310-825-9783)
    E-mail: mschibler@mednet.ucla.edu

    Electron Microscopy and Specimen Preparation
    For information, contact:
    Marianne Cilluffo, x59848 (310-825-9848)
    E-mail: mariannc@ucla.edu

    Microscopic Techniques and Histological Preparation
    For information, contact:
    Marianne Cilluffo, x59848 (310-825-9848)
    E-mail: mariannc@ucla.edu

    * The BRI Carol Moss Spivak Cell Imaging Core has moved in with the Advanced Light Microscopy Core, directed by Shimon Weiss and Laurent Bentolila. After a decade of operation on the first floor of the Gonda, joining these two facilities will result in a technically sophisticated confocal core on campus with considerably up-graded equipment and increased capacity compared to our current facility. The facility will have enhanced capability for FRET, FLIM, FCS, 2-photon microscopy and small animal imaging (zebrafish, flies and C. elegans). This core is centrally located on the B floor of the new California Nanosystems Institute (CNSI) and will continue to be available to all faculty laboratories at UCLA. Dr. Matt Schibler who has admirably run the BRI core since its inception will continue to train users and run/maintain equipment in the new facility. For concerned regular users of the core please contact Matt if you require details of instrument availability in March and April; the exact date for completion of the move is not yet established. There should be little downtime since most of the new instruments are up and running. You may need to learn slight differences between the new confocals even though they run on the same software. At this time no increase in core usage fees is anticipated.

    Other Cores:
    Biopolymer Laboratory
    Peptide synthesis, amino acid analysis, Edman sequencing, mass spectrometry.
    For information contact:
    Margaret Condron x62088 (310.206.2088)
    E-mail: condron@ucla.edu

    Pasarow Mass Spectrometry Laboratory
    For information, contact:
    Dr. Kym Faull X67881 (310-206-7881)
    E-mail: faull@chem.ucla.edu


    Research Resources Available:
    Postmortem Human Frozen Brain Tissue and Matched Cerebrospinal Fluid (CSF) and Blood are Available for Scientists to Search for Etiopathogeneses of Human Disease.

    The National Neurological Research Specimen Bank and the Multiple Sclerosis Human Neurospecimen Bank, located at VA West Los Angeles Healthcare Center, maintains a collection of quick frozen and formalin fixed postmortem human brain tissue and frozen cerebrospinal fluid (CSF) from patients with neurological diseases (including Alzheimer's Disease, amyotrophic lateral sclerosis, depressive disorder/suicide, epilepsy, Huntington's disease, multiple sclerosis, Parkinson's Disease, progressive supranuclear palsy, schizophrenia, stroke/CVA and other less common diseases). Full inventory is available upon request. Diagnoses are documented by clinical medical records and gross/microscopic neuropathology.

    Special features of the Bank are as follows:

    1). Serial digital images of coronal sections (7 mm thick and obtained before quick freezing) are available for selecting samples to be studied.
    2). Microscopic neuropathology is available on each dissected sample and the dissected sample's localization is sketched on the gross coronal section image from which it came.
    3). Plaques of demyelination are classified as active, chronic active or inactive, and a shipment includes adjacent normal appearing white and nearby gray matter from the same case (they serve as a type of control).
    4). Ice artifact is minimized and it does not interfere with in situ hybridization or in situ PCR or immunocytochemistry.
    5). Tissue samples have been used for harvesting enough mRNA for microarray assay plates.
    6). CSF cells and cell-free CSF are available pre- and postmortem as is serum, plasma and buffy coats. They are stored quick frozen (full inventory is available upon request).

    The Bank is supported by NIH (NINCDS/NIMH), the National Multiple Sclerosis Society and Veterans Affairs West Los Angeles Healthcare Center. For further information on tissues/CSF available and how to access them, contact:

    Wallace W. Tourtellotte, M.D., Ph.D.
    Neurology Research (127A)
    VA West Los Angeles Healthcare Center
    11301 Wilshire Blvd
    Los Angeles, CA 90073
    (310) 268_4638; fax: (310) 268_4638
    E-mail: wtourtel@ucla.edu
    web: www.loni.ucla.edu/~nnrsb/NNRSB


    Alzheimer's Disease Brain Tissue and CSF
    The Neuropathology Laboratory at UCLA Medical Center maintains a bank of frozen, formalin and paraformaldehyde-fixed and paraffin-embedded postmortem human brain tissues and frozen cerebrospinal fluid (CSF) from patients who die with Alzheimer's disease and other dementing and degenerative illnesses (including progressive supranuclear palsy, Parkinson's disease, fronto-temporal dementia), as well as control materials removed in a similar fashion from patients who are neurologically normal. Tissues are maintained as part of the NIA-funded Neuropathology Core functions of the UCLA Alzheimer's Disease Center. These tissues/fluids are available as a resource to investigators in any discipline. Pilot studies using the tissues/CSF to examine biomolecules that are of known importance in animal models and suspected significance in human neurodegenerative conditions are particularly encouraged. Every attempt will be made to provide research materials for worthwhile projects in a timely fashion. For further information on tissues/CSF available and how to access them, contact:

    Dr. Harry Vinters, Section of Neuropathology
    UCLA Medical Center, CHS 18-170
    Los Angeles, CA 90095-1732
    Phone: 310-825-6191; Fax: 310-206-8290
    E-mail: hvinters@mednet.ucla.edu

    EMPLOYMENT OPPORTUNITIES

    NIH-funded Postdoctoral Position-Neurophysiology

    A Postdoctoral position is available in the area of Neurophysiology, starting late winter/ early spring. The laboratory studies the cell physiology of gonadotropin releasing hormone (GnRH) neurons within an intact neural network during embryonic development using transgenic zebrafish. Candidates must have expertise in electrophysiology; optical imaging experience is a plus. Three years of NIH funding is available; salary is commensurate with experience. For additional information about the lab, refer tohttp://www.uclaaccess.ucla.edu/UCLAACCESS/web/Faculty.aspx?ri=166. Please send curriculum vitae along with the names and contact information for references to: Dr. Nancy Wayne; nwayne@mednet.ucla.edu.

    EMPLOYMENT CANDIDATES

    The BRI regularly receives letters and resumes from people looking for work in the field of neuroscience. Below is an abbreviated list of the candidates and the type of work they seek. Copies of their resumes are often available in our editorial office. If you are interested in one or more of these individuals, please contact them directly, or call the editorial office at x56055.

    Parwin Hakimi received a Bachelor of Arts degree in molecular and cell biology/ neurobiology from UC Berkeley in 2008, and would like to obtain a research associate position. With 10 years of previous experience in medical laboratories, Parwin has knowledge working in hematology, parasitology, virology, biochemistry, and bacteriology, as well as biology, biotechnology, chemistry and neurobiology. Parwin has experience using micropipettes, Western Blot, PCR, and many others techniques. In addition to lab experience, Parwin is experienced using Word, Excel and PowerPoint programs, and has experience in administrative, clerical and management areas. Parwin is available for administrative and/or scientific work as either a paid employee or volunteer. Parwin’s CV is available in the editorial office. Please contact Parwin directly at: parwin2001us@yahoo.com.

    Ricardo Murphy is a postdoctoral scientist currently seeking employment in neuroscience research. He is a biophysicist/physiologist with experience in the patch clamp technique, spectrofluorimetry, quantitative data analysis and mathematical/computational modeling. He would like to pursue a career in neuroscience research especially as approached from a biophysical or theoretical point of view. Dr. Murphy received his Ph.D. in plant science/biophysics from the University of East Anglia, United Kingdom. He has held research positions at the University of East Anglia, Trinity College, Dublin, Ireland, the University of Edinburgh, and the University of Oxford, U.K., and in the United States at the University of Colorado, Denver, the University of Delaware, Northeastern University, Rush Medical Center, and most recently at UCLA. A copy of Dr. Murphy’s CV is available from the editorial office. Please contact Dr. Murphy at ricardo_murphy@fastmail.fm.

    Susana Sandoval would like to obtain a research assistant position in a scientific research laboratory at UCLA. She graduated from UCLA in June 2008 with a Bachelor’s degree in biological sciences. She has completed courses in: Chemistry (general, organic, biochemistry); Biology (Ecology, Evolution & Biodiversity; Cells, Tissues & Organs; Genetics; Molecular); Math (Calculus --completed series);
    Physics (Mechanical, Electricity & Magnetism, Quantum) and laboratory courses in General Chemistry, Organic Chemistry, Biochemistry, Molecular Biology, Animal Physiology, Plant Physiology and Physics.
    Susana has skill in a number of laboratory techniques including: Electrophoresis on cellulose acetate; Agarose gel electrophoresis; SDS-PAGE; PCR; RT-PCR; Column chromatography; Animal cell homogenization; Spectrophotometric assay; Bradford; Protein purification; DNA purification; HPLC; TLC; NMR and IR spectroscopy; Compound synthesis; Compound identification; Immunostaining; Gas chromatography; Karyotype prep; Southern, Northern, and Western blot; ELISA; RIA; DNA sequencing; RFLP analysis; Titration; Distillation; Extraction; Rotary Evaporation; Error propagation, and computer skill in Word, Excel and Power Point. Susana will be applying to medical school for Fall of 2010 and would like to work in a research lab until that time. Susana’s CV is available in the editorial office. Please contact Susana directly at: suzieq1@ucla.edu.

    Linda Xu and Liza Verhaegh are two enthusiastic master’s students in Pharmaceutical Sciences at Utrecht University, the Netherlands, and they are interested in a 6-months research internship starting in September 2009. They are interested in human research and neuroscience. Their CV's are available in the editorial office. They will have their own funding while at UCLA. If interested, please contact them directly at:L.A.A.Verhaegh@students.uu.nlC.J.Xu@students.uu.nl.


    IMPORTANT NOTE: 

    Neuroscience News serves as the primary vehicle for disseminating information to the UCLA neuroscience community. It is published solely on the Brain Research Institute’s web site http://www.bri.ucla.edu and distributed to the BRI Calendar E-mail list. Please submit all information to the BRI editorial office, E-maillmaninger@mednet.ucla.edu, or call extension 56055 or 55061.

    Editor: Linda Maninger