Neuroscience News Winter 2002


ARCHIVED EDITION
Published by the UCLA Brain Research Institute 
WINTER, 2002 
Volume 11, No. 1

THE ARCS FOUNDATION AND THE BRAIN RESEARCH INSTITUTE

Seventy-four of the best and brightest science students from seven premier institutions of higher learning in southern California were saluted by the Los Angeles Founder Chapter of ARCS Foundation, Inc. (Achievement Rewards for College Scientists) at its 43rd Scholarship Recognition Luncheon at the California Club on Friday, November, 9, 2001.

Young, brilliant and in need of financial assistance to continue their education, these outstanding scholars received a record $1, 120,000 in scholarship monies from the ARCS Los Angeles Founder Chapter. The minimum scholarship given is $10,000. President Maggie Russell and luncheon chair, Edith Roberts opened the program and members of the Advisory Board introduced each of the scholars.

Receiving the funds for their students were the presidents and deans of the following institutions: California Institute of Technology; Harvey Mudd College; Keck School of Medicine, USC; Pomona College; Scripps Institution of Oceanography, UCSD; UCLA Brain Research Institute; and USC School of Engineering.

Since its inception in 1958, ARCS’ twelve chapters have raised $37.7 million, funding 8,570 scholarships. Of that amount, the Los Angeles Chapter has raised more than 13 million.

The partnership between the ARCS Foundation (Achievement Rewards for College Scientists) and the Brain Research Institute has been a long and fruitful one. For over thirty years, ARCS has supported graduate scholars in the UCLA Neuroscience Program. The brain is the ultimate frontier of scientific knowledge, and these young scientists will hold the key to coming advances that will shed light both on the normal workings of the brain and on brain disorders ranging from Parkinson’s and Alzheimer’s diseases to schizophrenia, depression and attention deficit disorder. The Brain Research Institute applauds the work and the vision of the ARCS Foundation, which has fostered the intellectual and professional development of some of the brightest students on the UCLA campus.
The faculty of the Brain Research Institute and the ARCS scholars join the BRI Director, Dr. Allan Tobin, in thanking the ARCS Foundation for their generous support.

BRI WELCOMES FIVE NEW MEMBERS

The Brain Research Institute welcomes Drs. Aaron Blaisdell, Assistant Professor of Psychology, Steven Berman, Associate Researcher, Department of Medicine, and NPI, Robert Greenberg, Adjunct Assistant Professor of Electrical Engineering, UCLA, and Associate Director, Alfred E. Mann Institute for Biomedical Engineering, USC, J. David Jentsch, Assistant Professor of Psychology, and Faustino Lopez, Assistant Professor of Psychiatry and Biobehavioral Sciences, as new members in the Institute.

Aaron Blaisdell received his Ph.D. degree from the State University of New York at Binghamton in 1999. He then completed a postdoctoral fellowship in the Department of Psychology at Tuffs University. He joined the UCLA Department of Psychology as assistant professor in July, 2001.

Dr. Blaisdell’s major area of research interest concerns animal learning and cognition. “My central interest lies in how animals represent their world, how these representations are built, and how they subserve information processes. To answer these questions, my research uses Pavlovian and instrumental conditioning procedures to study how laboratory rats, pigeons, and humans solve problems involving cause-effect relations, how they use temporal and spatial information (e.g., cognitive maps) to make response decisions, and how they construct more complex maps from simpler ones. Preliminary evidence indicates that animals use an inference-like process to build cognitive maps. These proximate mechanisms of behavior (i.e., information processing and response generation) will shed light on how the ultimate (i.e., evolutionary) function of behavior is served.”

After Peace Corps service as a science teacher in Africa, Steve Berman received a Ph.D. degree in Experimental Cognition from The City University of New York in 1986. He completed a postdoctoral fellowship at Columbia University's Psychiatric Institute, studying the development of electrophysiological signs of attention and memory during childhood. Dr. Berman came to UCLA in 1990 to characterize adolescent electrophysiological, neuropsychological, personality and genetic markers for alcoholism with Dr. Ernest Noble. Although this productive work continues, Dr. Berman also actively collaborates with Dr. Eran Zaidel in studies of the psychophysiology of hemispheric specialization/communication, and Dr. Emeran Mayer in the psychophysiology of functional disorders. In addition, he is working with Dr. Edythe London to study drug addiction with brain imaging, and Dr. Maura Mitrushina at California State University, Northridge to study electrophysiological correlates of early dementia.

Dr. Berman states, "The work I've been at the longest is the alcohol and drug abuse vulnerability studies. Starting from Dr. Nobles association of the A1 allele of the D2 dopamine receptor (DRD2) gene with a deficient dopaminergic system that predisposed to all forms of substance abuse (including obesity), I've been able to show 1) the first electrophysiological predictor of later drug use in adolescence, 2) the first electrophysiologic (P300) and neuropsychological (visuospatial ability) associates of a specific genetic polymorphism, and 3) the first gene-environment interaction in determination of behavioral markers of substance abuse vulnerability. All of our work suggests those at highest risk for substance abuse fit a self-medicating pattern of drug use long before addiction ensues. Recent work on the personality characteristic of novelty seeking discriminates between positive reinforcement sensation-seeking, and the negative reinforcement sensation-seeking more characteristic of severe substance abusers. Our newest project finds similar patterns for negative affect. We hope to soon apply these models to smoking behaviors. I'm also excited about ongoing work using brain imaging to reveal the changes during early abstinence in hospitalized methamphetamine abusers, and studies of functionally disordered gastrointestinal patients. In all of my work, I'm interested in combining the high temporal resolution of scalp-recorded electrical activity (ERPs) with the high spatial resolution of brain imaging to get a more complete picture of how our nervous system accomplishes a given task. After some success combining ERPs and positron-emission tomography (PET) to clarify hemispheric specialization of language subcomponents, we now plan to combine ERPs with fMRI to study IBS, the most common GI functional disorder. We have electrophysiological evidence that IBS patients are preattentively hyper-responsive to non-gut stimuli. Our first fMRI sessions validated our extensive PET studies of brain areas that respond to rectal pressure in these subjects, including amygdala deactivations that we believe to be antinociceptive. Combining event-related fMRI and ERPs will allow us to test pharmacologic probes in both human subjects and an in-house rodent model of IBS, and target the adrenergic and serotonergic systems that show maximal promise for intervention."

Robert Greenberg received his M.D. degree from Johns Hopkins University School of Medicine in 1996, and his Ph.D. degree in Biomedical Engineering from Johns Hopkins University in 1998. He then moved to California to become President and CEO of Second Sight, a company founded by Alfred E. Mann Foundation.

Describing his work at Second Sight, Dr. Greenberg states, “Second Sight, LLC was founded in 1998 to create a retinal prosthesis based on work done by various members of its team to provide sight to patients blinded from outer retinal degenerations, such as Retinitis Pigmentosa and Macular Degeneration. The company’s goal is to produce a system that will provide images to patients blinded by these conditions. Initial prototypes have been manufactured and tested in animals and will soon be tested in patients. Simple electrode arrays such as those in the initial prototypes have been shown in short-term experiments at Johns Hopkins Hospital to produce formed vision in patients with Retinitis Pigmentosa. From various tests, we have concluded that more pixels than are possible with these simple arrays are needed to yield images of reasonable quality. Second Sight is developing such more-advanced systems in collaboration with the Intraocular Retinal Prosthesis Group at the Wilmer Eye Institute at Johns Hopkins (now the Retina Institute at USC), Harvard-Massachusetts Eye and Ear Infirmary, MIT, and others. Second Sight, LLC is one of several medical device companies founded by Alfred Mann. Since 1972 Mr. Mann and his chief scientist, Joe Schulman have developed and successfully commercialized medical devices which have had a significant impact on the lives of many patients such as pacemakers and cochlear implants. By leveraging the knowledge gained by these endeavors, each new product has developed more quickly and to a higher level by not repeating early missteps. Second Sight has been able to leverage this wealth of knowledge in rapidly developing its first wireless implants.”

J. David Jentsch received his Ph.D. degree in neurobiology from Yale University School of Medicine in 1999. He then completed a postdoctoral fellowship in the Department of Psychiatry in the laboratory of Dr. Jane R. Taylor at Yale. He completed a second fellowship in the laboratory of Dr. Anthony Grace in the Department of Neuroscience at the University of Pittsburgh. In 2000, Dr. Jentsch returned to Yale as Associate Research Scientist in the Department of Psychiatry. Moving to California in 2001, Dr. Jentsch joined UCLA as Assistant Professor of Psychology.

Dr. Jentsch research interests center on the psychopharmacology of cognition. He states, “My research interests include the psychopharmacology of cognition and animal models of psychiatric disease. Both schizophrenia and attention deficit disorder are diseases characterized by well-known cognitive and attentional deficits and a constrained developmental emergence. Our research goals are therefore two-fold. First, we are exploring the neurochemical mechanisms that govern these processes in normal animal subjects (rodents and primates) and in others that have been rendered dysfunctional by administration of particular psychoactive substances known to evoke psychiatric episodes in human beings. Second, we are working to understand how developmental events, both pre- and post-natal, influence cognitive and attentional operations throughout the life span. Ultimately, we hope to provide a comprehensive analysis of brain mechanisms mediating cognition and attention across the full ontogenetic period.”

Faustino Lopez received his M.D. degree from the Universidad Complutense de Madrid, Spain, in 1985, and his Ph.D. degree in Neuroscience from the Universidad Autónoma de Madrid, Spain, in 1990. While completing his Ph.D. degree, Dr. Lopez received postdoctoral training at Servicio de Neurología Experimental, Departamento de Investigación de Hospital Ramón y Cajal de la Seguridad Social de Madrid, under the direction of Dr. García-Austt, working on rhythmicity of hippocampal neurons in the wakefulness-sleep cycle. Dr. Lopez came to UCLA in 1987 as a Visiting Research Physiologist working with Dr. Michael Chase, investigating the physiology and pharmacology of lumbar motoneurons during active sleep. In 1990, Dr. Lopez became Assistant Research Physiologist at UCLA. He then completed a postgraduate residency training program in psychiatry at the NPI in 1998, a fellowship in psychiatric research in 1999, and is currently Assistant Professor in the Department of Psychiatry and Biobehavioral Sciences.

Dr. Lopez is interested in the neurobiology of depression and sleep. He states, “I am interested in neurobiological mechanisms of antidepressant strategies. Currently, I am trying to determine the mechanisms of action of the antidepressant effects of sleep deprivation, using rats. I am concentrating on the serotonergic system, performing experiments on changes of serotonin release in sleep deprived rats.”
The Brain Research Institute is happy to welcome its newest members.

MARK YOUR CALENDARS

The Joint Seminars in Neuroscience series will resume April 2, 2002. Mark your calendars and plan to join us every Tuesday at 4:00 p.m. in the Louis Jolyon West Auditorium (C8-183 NPI).

JOINT SEMINARS IN NEUROSCIENCE SPRING 2002

April 2, 2002 
ANTHONY T. CAMPAGNONI, Ph.D.
Professor of Neuroscience, Neuropsychiatric Institute, David Geffen School of Medicine at UCLA
The 13th Annual H.W. Magoun Lecture
“The Many Faces of the Myelin Basic Protein Gene: From Reverse Genetics to Cortical Development”

April 9, 2002 
JENNIFER L. RAYMOND, Ph.D.
Department of Neurobiology, Stanford University School of Medicine, California
“Cerebellar Plasticity and Motor Learning”

April 16, 2002
NELSON P. SPRUSTON, Ph.D.
Department of Neurobiology and Physiology, Institute for Neuroscience, Northwestern University, Evanston, Illinois
“Dendritic Excitability and Synaptic Plasticity in the Hippocampus”

April 23, 2002 
RANDOLPH BLAKE, Ph.D.
Vanderbilt Vision Research Center, Vanderbilt University, Nashville, Tennessee
“Psychoanatomy of Human Vision”

April 30, 2002
THOMAS C. SUDHOF, M.D.
Center for Basic Neuroscience and Howard Hughes Medical Institute, The University of Texas Southwestern Medical Center, Dallas
“Molecular Mechanisms of Neurotransmitter Release at a Central Synapse”

May 7, 2002
CRISTINA ALBERINI, Ph.D.
Department of Physiology and Biophysics, Mount Sinai School of Medicine, New York
“Transcription Regulation in Memory”

May 14, 2002
ROBERT H.-P. CHOW, M.D., Ph.D.
Department of Physiology and Biophysics, Keck School of Medicine, University of Southern California, Los Angeles
“Functional and Spatial Segregation of Secretory Vesicles According to Age”

May 21, 2002 
MICHAEL J. MEANEY, Ph.D.
Professor, Departments of Psychiatry, and Neurology & Neurosurgery; Director, McGill Program for the Study of Behaviour, Genes and Environment, McGill University, Montreal, Canada
“Maternal Care, Gene Expression and the Development of Individual Differences in Responses to Stress”

May 28, 2002
JANIS C. WEEKS, Ph.D.
Institute of Neuroscience, University of Oregon, Eugene
“Thinking Globally, Acting Locally: Steroid Hormones, Synaptic Plasticity and Neuronal Death”

June 4, 2002
LEARNING & MEMORY SYMPOSIUM (Jules Stein Auditorium) 
Registration Required: http://www.silvalab.com/symposium.htm

June 11, 2002 
The 10th Annual Samuel Eiduson Student Lecture
Interdepartmental Ph.D. Program for Neuroscience, UCLA
“TBD”

The Joint Seminars in Neuroscience are sponsored by The Brain Research Institute and the Neuropsychiatric Institute; co-sponsored by the Interdepartmental Programs for Neuroscience, the Mental Retardation Research Center, and the Departments of Anesthesiology, Neurobiology, Neurology, Pathology and Laboratory Medicine, Psychiatry and Biobehavioral Sciences, Psychology, Physiology, Physiological Science, Ophthalmology, and Surgery/Neurosurgery.
Category 1 Continuing Medical Education (CME). This is an activity offered by the UCLA NPI&H, a CMA-accredited provider. Physicians attending this course may report up to 1 hour of Category 1 credit per course toward the CMA’s Certificate in Continuing Medical Education and the AMA’s Physician’s Recognition Award.

THE BRAIN RESEARCH INSTITUTE CORE FACILITIES SERVICES

Carol Moss Spivak Cell Imaging Facility 
Confocal Microscopy 
For information, contact: 
Dr. Matt Schibler X59783
E-mail: mschibler@mednet.ucla.edu

Electron Microscopy and Specimen Preparation 
For information, contact: 
Brigitta Sjostrand X68054 
E-mail: birgitta@ucla.edu

Microscopic Techniques and Histological Preparation
For information, contact: 
Sharon Sampogna X59848 
E-mail: sampogna@ucla.edu

Other Cores: 
Pasarow Mass Spectrometry Laboratory 
For information, contact: 
Dr. Kym Faull X67881 
E-mail: faull@chem.ucla.edu

RESEARCH RESOURCES AVAILABLE-

Postmortem Human Frozen Brain Tissue and Matched Cerebrospinal Fluid (CSF) and Blood are Available for Scientists to Search for Etiopathogeneses of Human Disease. 
The National Neurological Research Specimen Bank and the Multiple Sclerosis Human Neurospecimen Bank, located at VA West Los Angeles Healthcare Center, maintains a collection of quick frozen and formalin fixed postmortem human brain tissue and frozen cerebrospinal fluid (CSF) from patients with neurological diseases (including Alzheimer's Disease, amyotrophic lateral sclerosis, depressive disorder/suicide, epilepsy, Huntington's disease, multiple sclerosis, Parkinson's Disease, progressive supranuclear palsy, schizophrenia, stroke/CVA and other less common diseases). Full inventory is available upon request. Diagnoses are documented by clinical medical records and gross/microscopic neuropathology.

Special features of the Bank are as follows:

1). Serial digital images of coronal sections (7 mm thick and obtained before quick freezing) are available for selecting samples to be studied.

2). Microscopic neuropathology is available on each dissected sample and the dissected sample's localization is sketched on the gross coronal section image from which it came.

3). Plaques of demyelination are classified as active, chronic active or inactive, and a shipment includes adjacent normal appearing white and nearby gray matter from the same case (they serve as a type of control).

4). Ice artifact is minimized and it does not interfere with in situ hybridization or in situ PCR or immunocytochemistry.

5). Tissue samples have been used for harvesting enough mRNA for microarray assay plates.

6). CSF cells and cell-free CSF are available pre- and postmortem as is serum, plasma and buffy coats. They are stored quick frozen (full inventory is available upon request).

The Bank is supported by NIH (NINCDS/NIMH), the National Multiple Sclerosis Society and Veterans Affairs West Los Angeles Healthcare Center.
For further information on tissues/CSF available and how to access them, contact:
Wallace W. Tourtellotte, M.D., Ph.D. 
Neurology Research (127A) 
VA West Los Angeles Healthcare Center 
11301 Wilshire Blvd 
Los Angeles, CA 90073 
(310) 268_4638; fax: (310) 268_4638 
E-mail: wtourtel@ucla.edu
web site: www.loni.ucla.edu/~nnrsb/NNRSB

ALZHEIMER'S DISEASE BRAIN TISSUE and CSF

The Neuropathology Laboratory at UCLA Medical Center maintains a bank of frozen, formalin and paraformaldehyde-fixed and paraffin-embedded postmortem human brain tissues and frozen cerebrospinal fluid (CSF) from patients who die with Alzheimer's disease and other dementing and degenerative illnesses (including progressive supranuclear palsy, Parkinson's disease, fronto-temporal dementia), as well as control materials removed in a similar fashion from patients who are neurologically normal. Tissues are maintained as part of the NIA-funded Neuropathology Core functions of the UCLA Alzheimer's Disease Center. These tissues/fluids are available as a resource to investigators in any discipline. Pilot studies using the tissues/CSF to examine biomolecules that are of known importance in animal models and suspected significance in human neurodegenerative conditions are particularly encouraged. Every attempt will be made to provide research materials for worthwhile projects in a timely fashion. For further information on tissues/CSF available and how to access them, contact: 
Dr. Harry Vinters, Section of Neuropathology 
UCLA Medical Center, CHS 18-170 
Los Angeles, CA 90095-1732
Phone: 310-825-6191; Fax: 310-206-8290 
E-mail: hvinters@mednet.ucla.edu

FELLOWSHIPS, GRANTS and AWARDS

POSTDOCTORAL POSITIONS OPEN
Herbert Weiner Distinguished Fellow in Psychoneuroimmunology
The Norman Cousins Center for Psychoneuroimmunology, Neuropsychiatric Institute, UCLA sponsors this interdepartmental program that offers post-doctoral research training and collaborations with faculty from the Neuropsychiatric Institute, Brain Research Institute, and the Departments of Psychology, Medicine, and Immunology at UCLA. The work of the Center focuses on the interactions among the environment, brain, behavior, and the immune- and neuroendocrine systems, and their clinical implications. Innovative basic, clinical, or experimental studies that deal with the course of disease mediated by the immune system are encouraged. Successful candidates will have capacity to conduct hypothesis-driven interdisciplinary research on a topic of his/her choice. Post-doctoral salary support and up to $20,000 for research costs are provided. The deadline is open Interested applicants should contact:
Michael Irwin, M.D. 
Director, Cousins Center for Psychoneuroimmunology 
Neuropsychiatric Institute
300 Medical Plaza (3-109) 
Los Angeles, CA 90095 
Phone: (310 825 8281) 
E-mail: mirwin1@ucla.edu

Postdoctoral Position in Neural Repair
There are ongoing pre- and postdoctoral positions available on the Training Program in Neural Repair. Priority will be given to outstanding candidates that have already obtained a Ph.D. degree, and are ready to start early in the academic year. Applicants who are U.S. citizens or already have a green card (no pending application) will be considered. Stipend levels are based on NIH guidelines. Awards will be made for a one year period, with additional support available on a competitive basis but only if an alternate source of support is pending. 
Candidates should submit the following material for consideration: a nomination letter from their UCLA mentor; a two page description of the research project indicating its relevance to neural repair; a description of long-term goals; a curriculum vitae, and two letters of recommendation by individuals other than the mentor. Applications should be submitted to: 
M-F Chesselet, M.D., Ph.D. 
Program Director, Department of Neurology 
David Geffen School of Medicine at UCLA 
Reed Neurological Research Center, B114 
710 Westwood Plaza 
Los Angeles, CA 90095-1769 
(on campus, use campus code 176919) 
E-mail: mchesselet@mednet.ucla.edu

John E. Fogarty; NIH Visiting Scholars Program for Foreign Scientists

* Visiting Fellows Awards
* Visiting Scientists Awards

Targeted Fields: Research in the biomedical sciences. 
Eligibility: Visiting Fellows: Visiting fellows must have a doctoral degree or equivalent in the health sciences and not more than five years of relevant postdoctoral research experience at the start of the fellowship period. U.S. citizens are not eligible for the Visiting Fellow award. 

Visiting Scientists: Visiting Scientists with three or more years of relevant post-doctoral research experiences are eligible for the following types of appointments: Research Fellow (VP), Clinical Fellow (VP), Staff Scientist (VP), Staff Clinician (VP), Investigator (VP), and Senior Investigator (VP).

Stipend: Visiting Fellows: Visiting fellows receive a monthly stipend during the award period to cover living expenses. The stipend level is determined by the number of years of relevant postdoctoral research experience. Visiting Fellows are not considered employees of the NIH. 

Visiting Scientists: Visiting Scientists are appointed to conduct health-related research. They are considered employees of the NIH, receive a salary and, depending on the length of appointment, receive most of the benefits available to employees of the U.S. Government. Visiting Scientists appointments generally are made for up to two years but may be made for a shorter period. Appointments may be renewed; however, the total length of an appointment may not exceed five years. All renewals are subject to applicable visa restrictions.

Deadline Date: Open Deadline - Interested Fellows and Scientists may submit necessary information at any time. Successful candidates for the NIH Visiting Program will be notified of selection for a fellowship award or 
appointment and the date it begins in a letter from the Director of the Fogarty International Center, NIH.

Program Summary: The NIH Visiting Program provides opportunities for foreign scientists to train and conduct collaborative research at the National Institute of Health (NIH), the principal agency of the U.S. Government responsible for conducting and supporting biomedical research. Each year, more than 2,000 scientists from other nations conduct research in the basic and clinical science laboratories on the NIH campus in Bethesda, Maryland, and in several field units around the country. The Visiting Program is open to scientists at all career levels. There are two categories of Visiting Program participants: Visiting Fellows, who receive awards for research training, and Visiting Scientists, who receive appointments to conduct research. Each participant works closely with a senior NIH investigator who serves as supervisor or sponsor during the period of award or appointment.

Application Procedures: An award or appointment to the Visiting Program must be requested by a senior scientist in one of the NIH's intramural laboratories and is offered based on the candidate's qualifications and the research needs of the host laboratory. The NIH senior scientist serves as the participant's sponsor and supervisor during the period of award or appointment. Individuals interested in a Visiting Program fellowship award or appointment should write to NIH senior scientists working in the same research field, enclosing a resume and brief description of their particular research area. Information about the research being conducted by NIH scientists and their names may be obtained through the NIH's CRISP system. Enter your search terms; under activity select "intramural"; then submit query. For complete guideline and application information please contact: 

International Services Branch 
Fogarty International Center 
National Institutes of Health 
Building 16A, Room 101 
16A Center Dr. MSC 6710 
Bethesda, MD 20892-6710 
http://www.nih.gov/fic/services/program.html

UCLA Human Gene Medicine Program
2002 Research Fellowship/Seed Grant Program

Eligibility: All applicants must be UCLA faculty members. 
Program Summary: Fellowship/Seed Grants are available for members of the wider UCLA community to support innovative research in areas of gene therapy, including vector design and development, gene delivery and expression, and preclinical testing of gene therapy strategies. Applications that promote collaboration between basic and preclinical programs are particularly encouraged, as are those which explore novel gene therapy approaches and new areas of application. Proposals dealing with the application of gene transfer to purely scientific problems are not generally viewed favorably. The goal is to encourage both junior and experienced investigators to initiate projects that could eventually be integrated into a clinical gene therapy program in any field of medicine, and that could compete successfully for extramural funds in the near future. Investigators who have not been funded previously through this program will be favored. In all circumstances, the quality of the science and the clinical applicability will be the deciding criteria. 

Grants up to $30,000 are awarded for a one-year period to support a pre- or postdoctoral fellow or research assistant, or to purchase supplies or small pieces of equipment (less than $1,000). They cannot be used to support the salary of the principal investigator, to purchase major items of equipment, or other purposes. The program is not intended to support or supplement projects presently funded from other sources or to act as a continuing source of funds for any one laboratory.

To Apply: There are no specific application forms. The application should not exceed 5 pages in length. The title page should contain the name of the P.I., a complete mailing address (with campus mail code, phone, fax and e-mail address) and a half-page abstract that clearly states the problem, its importance to gene therapy, the specific aims of the project, and the proposed experimental approach. The body of the application should not exceed 4 pages for Background, Preliminary Data (if any), Proposed Experiments, and References. The application must be accompanied by NIH-style Biosketches, Other Support and Budget Pages and one standard campus mail envelope with your campus mailing address and mail code on it (for notification purposes). Ten copies of the application should be submitted to the UCLA Human Gene Medicine Program at the address listed below.
Applications will not be funded until approval is obtained from the appropriate committees dealing with animals, radiation, Human Subjects, and Hazardous Materials. 

Due Dates: May 1, 2002 (start date of July 1, 2002); November 1, 2002 (start date of January 1, 2003). 
For More Information: 
Dr. Graeme Dougherty
Department of Radiation Oncology 
UCLA Medical Center
Room B3-109 CHS 
10833 Le Conte Avenue 
Los Angeles, CA 90095-1714 
(campus mail code 171415) 
Phone: (310) 206-8733 
E-mail: graeme@radonc.ucla.edu

EMPLOYMENT CANDIDATES

The BRI regularly receives letters and resumes from people looking for work in the field of neuroscience. Below is an abbreviated list of the candidates and the type of work they seek. Copies of their resumes are often available in our editorial office. If you are interested in one or more of these individuals, please contact them directly, or call x56055. 

Tiffany Palanca is a freshman at Oberlin College, originally from Los Angeles. She would like to obtain a summer research opportunity/lab experience while home this summer. She has volunteered in hospitals, including UCLA, and helped neuroscience honors students on their lab projects this past January. She would like to volunteer, observe, and help out in any way possible. Her previous volunteer experience includes: Summer 1997--Pediatrics and Plant Services at Kaiser Permanente Hospital Woodland Hills; Summer 1998, 1999, 2000-- Gastroenterology at Kaiser Permanente Hospital Woodland Hills; Summer 1999--Neurological Services at UCLA Medical Plaza; Fall 2001-- Surgical Oncology at Community Health Partners Hospital in Lorain, Ohio. In addition, Tiffany has taken a number of relevant college courses including: Fall 2001--Chemistry 101, Structure and Reactivity, with a weekly lab; January 2002 - Assisted in Senior Honors Neuroscience Research, “The role of nitric oxide in long-term depression in rat hippocampus and in glutamate transport;” Spring 2002--Chemistry 102: Chemical Principles- Equilibrium, thermodynamics, reaction rates and mechanisms, atomic and molecular orbitals with a weekly lab; Biology 120-- Genetics, Evolution and Ecology- This course provides an integrated introduction to key biological principles of genetics, ecology, and evolution. The weekly labs feature exercises and discussion designed to develop critical thinking and problem-solving skills in data analysis and interpretation. Preserved animals are dissected in some laboratories. 

Tiffany can be reached directly at Oberlin College (440) 775-6818; or at her California home, (818) 709-4954.

 

IMPORTANT NOTE:

Neuroscience News serves as the primary vehicle for disseminating information to the UCLA neuroscience community. It is published solely on the Brain Research Institute's web site http://www.bri.ucla.edu and distributed to the BRI Calendar E-mail list. Please submit all information to the BRI editorial office, E-mail lmaninger@mednet.ucla.edu, or call extension 56055 or 55061.

Editor: Linda Maninger