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Research and Career Opportunities

 

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Post-Doctoral Positions

POSTED FEBRUARY 24, 2017
Postdoctoral Position in Functional Neuroimaging of Trauma - Department of Psychiatry - University of California, San Francisco

We seek a highly talented and motivated postdoctoral researcher to join San Francisco VA/UCSF to conduct fMRI project on neural mechanisms of pain and emotion in Veterans with combat trauma.  The overarching aim of the project is to build neural models predicting pain resilience and pain vulnerability in those who suffered trauma during combat or related experience.  Your duties will be supervising data collection, conducting advanced fMRI analyses, including brain connectivity and machine learning, and publishing.  There will be ample opportunity to develop your own research questions and focus within this large-scale multidisciplinary project.

In addition, you will have the opportunity to supervise students and research assistants who will conduct recruitment and data collection.  You will be joining the Emotion and Pain Laboratory led by Dr. Irina Strigo.  Our group investigates brain networks that process pain and emotion in individuals with depressive, anxiety disorders, chronic pain, and traumatic brain injury.  In addition, we seek to understand how individual differences in paid response relate to pain chronification in these individuals.  You will be given the opportunity to regularly present your work at international conferences and meetings.  Also, in order to develop your own research agenda, we will encourage and support you in applying for competitive career development fellowships towards the end of the project.

You should have a PhD degree (or equivalent) and experience in one or more of the following:

  • Neuroimaging
  • Psychology
  • Neuroscience Modeling
  • Statistics
  • Computer Science
  • Bioengineering
  • Cognitive Neuroscience
  • Related Fields

Candidates with a strong background in affective /cognitive neuroscience and experience with psychophysiological measures and advanced neuroimaging data analyses, computational modeling and machine learning, UNIX/Python/C++ programming are particularly encouraged to apply.

Candidates must be U.S. citizens.

The position is available immediately, and applications will be accepted until the position is filled.

To apply, please send a brief statement of research interest and goals, any selected reprints, CV, and names and addresses of three references.

For additional information or to apply contact:

Irina Strigo, Ph.D.
Department of Psychiatry
UC San Francisco
Irina.strigo@ucsf.edu
 

POSTED JANUARY 12, 2017
3-Year Post-Doc Imperial Level B Salary £37,970 - £41,100 pa Inclusive, London, UK

An exciting opportunity for a Postdoctoral Research Fellowship is available in the Laboratory of Synaptic Plasticity and Repair of Imperial College London.

We use an interdisciplinary approach, combining advanced optical imaging methods, including multiphoton and superresolution microscopy, optogenetics and in vivo calcium imaging with electrophysiology and molecular genetics, to study the regulation of axon and synaptic connectivity in the adult neocortex, a brain region affected in numerous neurodevelopmental and degenerative diseases as well as acute injuries, which are incurable to date.

For more information, visit our Imperial College London and personal www.DePaolaLab.com web pages.

Requirements for the Position:  PhD degree and strong publication record.

Required Expertise:  Cellular and/or molecular neuroscience and mouse genetics.  In vivo optogenetics, electrophysiology or calcium imaging experience will be an advantage.

We are looking for highly motivated and enthusiastic researchers with a strong interest in using cutting-edge optical imaging and molecular genetic methods to advance our knowledge of how synaptic connectivity is regulated in both normal and neuropathological settings.

Applications, including CV, list of publications and statement of research interests should be sent to Dr. Vincenzo De Paola (v.depaola@lms.mrc.ac.uk).  Applicants should arrange to have at least two confidential letters of reference sent by referees to this email address.
 

POSTED JANUARY 9, 2017
Postdoctoral Fellow Neuroscience for Janssen Research and Development, L.L.C., a Johnson and Johnson Company

Janssen Research and Development, L.L.C., a Johnson and Johnson company, is recruiting for a postdoctoral fellow for the Neuroscience Discovery group, located in La Jolla, CA.

Janssen Research and Development, L.L.C. develops treatments that improve the health and lifestyles of people worldwide.  Research and development areas encompass novel targets in neuropsychiatry neurologic disorders, oncology, infectious diseases, metabolic disorders and immunologic disorders.  We have produced and marketed many first-in-class prescription medications and are poised to serve the broad needs of the healthcare market - from patients to practitioners, from clinics to hospitals.

Thriving on a diverse company culture, celebrating the uniqueness of our employees and committed to inclusion, Janssen Research and Development, L.L.C. is proud to be an equal-opportunity employer.

We are seeking a highly motivated neuroimmunologist to join the Neuroscience Discovery research team, devoted to the discovery and development of novel therapeutics for neurological and neuropsychiatric disorders.  The successful candidate must be well-versed in immunology and have experience working with CNS models.  She/he will undertake challenging scientific questions in the area of neuro-immune interactions, with specific focus on the borders of the brain, i.e. meninges, choroid plexus, blood-brain barrier.  A proven background in adaptive and particularly humoral immunity is required for this position.  The candidate must demonstrate unconventional scientific curiosity, intellectual hunger, be innovative, and be self-driven to take on challenging projects.  A desire to complete projects within a specific timeframe of 2-3 years is a must.  Postdoctoral fellows are highly encouraged to publish their science in top tier journals with high impact factor.

Qualifications

The qualified candidate will have a Ph.D. degree in immunology, neuroscience, pharmacology or interdisciplinary biology with approximately 0-4 years of postgraduate experience.  The candidate must be comfortable working in the laboratory and should be proficient with multicolor flow cytometry, immune cell culture and cell isolation techniques (sorting is a definite plus); in addition, prior experience with imaging-related techniques like immunofluorescent labeling of cells and tissues, confocal microscopy and/or 2-photon microscopy is a definite plus.  In-vivo skills such as familiarity with injection routes (oral gavage, i.p., s.c., tail vein) and experience in aseptic surgical techniques are mandatory for the position.  The candidate must be motivated to learn new techniques at a fast pace, innovate, and have a positive attitude towards experimental science.

The position will be located in La Jolla, CA.

Click here if you are interested in applying for this position.

Primary Location
United States-California-San Diego
Organization
Janssen Research and Development, L.L.C. (6084)
Job Function
Administration
 

POSTED NOVEMBER 30, 2016
Postdoctoral Position Available in the Laboratory of Dr. Gerald Lipshutz at UCLA

A postdoctoral fellowship position is available in the Lipshutz Laboratory in the Intellectual and Developmental Disabilities Research Center at UCLA.  The goal of this project is to investigate the decreased intrinsic excitability, altered functional synaptic transmission, decreased dendritic arborization and decreased synapse density in Arginase Deficiency, a urea cycle disorder that leads to continued cognitive decline (Cantero G, et al. Rescue of the Functional Alterations of Motor Cortical Circuits in Arginase Deficiency by Neonatal Gene Therapy, J Neurosci. 2016 Jun 22;36(25):6680-90).  Methods will include brain slice patch-clamp recordings from cortical neurons (including tonic inhibition, intrinsic excitability, paired recording and examination of effects by gene therapy), as well as electron microscopy, immunohistochemistry, and animal behavioral testing.  The laboratory has access to equipment for custom electrophysiology along with the advanced imaging technologies of the Electron Imaging Center for NanoMachines (EICN) at UCLA.  As we have developed both CRISPR/Cas9 methods of genomic addition (Lee PC, et all. Restoring Ureagenesis in Hepatocytes by CRISPR/Cas9 mediated Genomic Addition to Arginase-deficient Induced Pluripotent Stem Cells, Molecular Therapy--Nucleic Acids 20165, el (in press)) and neuronal development from human iPSCs, such technologies will allow us to examine for resolution of abnormalities by high throughput screening that may alter the natural course of this disorder.

UCLA offers a rich academic environment where there are extensive opportunities for collaboration with an outstanding neuroscience faculty.  In addition, it offers all the cultural advantages of a major city with endless activities in a mild environment.

Successful candidates with have a Ph.D. or M.D.-Ph.D. degree and advanced experience in neuronal patch-clamp electrophysiology and at least some experience with statistical analysis.  Adequate NIH-supported funding exists in the laboratory but postdoctoral fellows will be encouraged to apply for independent funding.  We are especially interested in candidates who have a desire to develop independent careers as investigators.

Applicants should send their curriculum vitae with a list of publications, references and a letter of interest by email to:  glipshutz@mednet.ucla.edu
 

Research Assistant Positions

 

POSTED JANUARY 12, 2017
ARUK-funded Research Assistant in Cellular Neuroscience, Up to 6-Month Research Assistant Imperial £26,650 - £29,410 pa Inclusive, London, UK

An excellent opportunity for a Research Assistant is available in the Laboratory of Synaptic Plasticity and Repair of Imperial College London.

We use an interdisciplinary approach, combining advanced optical imaging methods, including multiphoton and superresolution microscopy, optogenetics and in vivo calcium imaging with electrophysiology and neuroanatomical reconstructions, to study the regulation of axon and synaptic connectivity in the adult neocortex, a brain region affected in numerous neurodevelopmental and degenerative diseases as well as acute injuries, which are incurable to date.

For more information, visit our Imperial College London and personal www.DePaolaLab.com web pages.

Requirements for the Position:  Bachelor degree and/or Master's degree.

Required Expertise:  Data management, visualization, analysis, segmentation and interpretation.  Image analysis software experience (e.g. NeuronStudio, Imaris, imageJ, Vaa3D, Volocity, custom-made).  Experience in software development (i.e. programming) and in the analysis of longitudinal structural and/or functional imaging experiments will be an advantage.

We are looking for highly motivated and enthusiastic researchers with a strong interest in data management and analysis in the field of neuronal imaging to advance our knowledge of how synaptic connectivity is regulated in both normal and neuropathological settings.

Applications, including CV and statement of research interests should be sent to Dr. Vincenzo De Paola (v.depaola@lms.mrc.ac.uk).