Correlate Brain Activity with fMRI Signals
By Robert Preidt
THURSDAY, Aug. 4 (HealthDay News) -- The first study to
show a link between functional magnetic resonance imaging
(fMRI) and actual brain cell electrical activity in humans
validates fMRI as a neural research and clinical tool,
according to researchers in the United States and Israel.
University of California, Los Angeles researchers
first recorded the responses of single brain cells in
the auditory cortex of two patients wired with intracranial
electrodes as they viewed a nine-minute movie clip.
The UCLA team then used this data to accurately
predict the fMRI signals collected from 11 different people
as they watched the same nine-minute movie clip while
in an MRI scanner thousands of miles away in Israel.
The study appears in the Aug. 5 issue of
the journal Science.
"Although functional magnetic resonance
imaging is widely accepted as an important research tool,
the relationship between fMRI signals in the human brain
and the underlying neuronal activity has been unclear
until now," study co-investigator Dr. Itzhak Fried,
professor-in-residence of neurosurgery and psychiatry
and biobehavioral sciences at UCLA, said in a prepared
"Our findings help validate the use
of fMRI in a wide array of leading-edge neuroscience research
in humans. However, additional research will be needed
to see whether this striking correlation between fMRI
signals and single neuronal activity also exists in brain
regions other than the auditory cortex," Fried said.
The American College of Radiology and the
Radiological Society of North America have more about
Original source: http://www.forbes.com