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As an emerging research model, zebrafish provide the following advantages: Zebrafish have been targeted by the Genome Project with anticipated completion of the genome sequence in 2004-05; development occurs ex-utero; transgenics can be made readily, and GFP-labeled cells can be followed during development; ENU mutagenesis can be conducted providing the opportunity for realistic genetic screens. A number of BRI faculty, as well as postdoctoral and graduate students would like to explore the possibility of using this model to address questions concerning development, behavior, gene regulation and the fate of targeted cell types. The affinity group will provide a forum for interested researchers within the BRI to explore the power and pitfalls of using this model. The meetings will alternate between journal clubs and short informal presentations from faculty within UCLA or surrounding institutions who are using zebrafish for their research. The presentations will be followed by open discussions. The affinity group will provide collaborative opportunities for UCLA researchers already using zebrafish in their research and furthermore give alternatives to those currently using either less relevant invertebrate models, or expensive and restrictive mammalian models.

· Affinity Group Summary
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Affinity Group Participants
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Samuel Eiduson - 1918-2007

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