9:00 am - 5:30 pm, Neuroscience Research Building Auditorium The Integrative Center for Learning and Memory
Twelfth Annual Southern California Learning & Memory Symposium
9:00 Welcome and Opening Remarks
Alcino J. Silva, Ph.D., Departments of Neurobiology, Psychiatry & Biobehavioral Sciences, and Psychology, University of California, Los Angeles
Session 1 Chair: Michael Fanselow, Ph.D., Departments of Psychology, and Psychiatry & Biobehavioral Sciences, University of California, Los Angeles
9:05 Noradrenergic Control of Cortical Membrane Potential Dynamics in Awake Behaving Mice
Peyman Golshani, M.D., Ph.D., Department of Neurology, University of California, Los Angeles
9:35 Information-Theoretic Principles in Learning and Decision-Making
Tatyana Sharpee, Ph.D., Computational Neurobiology Laboratory, Salk Institute for Biological Studies, La Jolla, California
10:05 Strategies for Maintaining Cognitive Health
Gary Small, M.D., Department of Psychiatry & Biobehavioral Sciences, UCLA Longevity Center, University of California, Los Angeles
10:35 Coffee Break
Session 2 Chair: Dean Buonomano, Ph.D., Departments of Neurobiology, and Psychology, University of California, Los Angeles
11:00 Deep Brain Stimulation, Memory Enhancement, and Hippocampal Theta-Gamma Coupling
Nanthia Suthana, Ph.D., Departments of Psychology, and Neurosurgery, University of California, Los Angeles
11:30 The Reactivation of Cortical Plasticity by Inhibitory Neuron Transplantation
Sunil Gandhi, Ph.D., Department of Neurobiology and Behavior, University of California, Irvine
12:00 Regulation of Inhibitory Synapses by the Transcription Factor Npas4
Brenda Bloodgood, Ph.D., Biological Sciences, University of California, San Diego
12:30 Lunch Break
Session 3 Chair: David Glanzman, Ph.D., Departments of Integrative Biology & Physiology, and Neurobiology, University of California, Los Angeles
2:00 Dissecting a Learning Circuit in C. elegans
Sreekanth Chalasani, Ph.D., Molecular Neurobiology Laboratory, Salk Institute for Biological Studies, La Jolla, California
2:30 Synaptic Signaling Networks and Neurodevelopmental Disease
Marcelo Coba, Ph.D., Department of Psychiatry and the Behavioral Sciences, Zilkha Neurogenetic Institute, Keck School of Medicine, University of Southern California, Los Angeles
3:00 Optogenetics: Deconstruction of Diseased Brain Circuitry and Tool Development
Viviana Gradinaru, Ph.D., Division of Biology, California Institute of Technology, Los Angeles
3:30 Coffee Break
Session 4 Chair: Tom O’Dell, Ph.D, Department of Physiology, University of California, Los Angeles
4:00 The Role of Hippocampal Adult Neurogenesis in Context Discrimination
Fred (Rusty) Gage, Ph.D., Laboratory of Genetics, Salk Institute for Biological Studies, La Jolla, California
4:30 Network-Level Analysis of Basal Ganglia Circuitry during Reward-Based Learning
Sotiris Masmanidis, Ph.D., Department of Neurobiology and California NanoSystems Institute, University of California, Los Angeles
9:00 am - 5:30 pm, Neuroscience Research Building Auditorium The Integrative Center for Learning and Memory
Twelfth Annual Southern California Learning & Memory Symposium
5:00 Neuron-Specific Nucleosome Remodeling: A Missing Link in Our Understanding of Intellectual Disability Disorders
Marcelo Wood, Ph.D., Department of Neurobiology and Behavior, Center for the Neurobiology of Learning & Memory, University of California, Irvine
(Sponsored by the UCLA Clinical and Translational Science Institute and the UCLA Brain Research Institute)
11:00 am – 12:00 pm, Gonda 1st Floor Conference Room, 1357
No Human Genetics Seminar.
3:00 pm – 4:00 pm, C-128 RNRC
No Alzheimer’s Disease Research Forum [ADRF].
TUESDAY, June 4, 2013
11:00 am – 12:00 pm, Jolyon West Auditorium, C8-183 Semel Institute (formerly NPI)
No Semel Institute for Neuroscience & Human Behavior Grand Rounds.
4:00 pm – 5:00 pm, Neuroscience Research Building Auditorium
Transducing Ca2+ Signals to Exocytosis
Edwin R. Chapman, Howard Hughes Medical Institute, and Department of Physiology, University of Wisconsin-Madison
(Joint Seminars in Neuroscience)
WEDNESDAY, June 5, 2013
9:00 am – 10:00 am, Neuroscience Research Building Auditorium
Title and Speaker to be Determined
(Neurology Grand Rounds)
4:00 pm – 5:00 pm, Gonda First Floor Conference Room, 1357
Antisense Oligonucleotide Knockdown of Alpha-Synuclein after Deficit Onset Improves Behavior and Neuropathology in Over-Expressing Mice
Nick Franich, Postdoctoral Scholar, Chesselet Laboratory, Department of Neurology, UCLA
(Center for the Study of Parkinson’s Disease Colloquium)
THURSDAY, June 6, 2013
12:00 pm – 1:00 pm, Gonda First Floor Conference Room, 1357
The Genetic Architecture of Bipolar Disorder and Its
Component Traits
Nelson Freimer, Maggie G. Gilbert Professor of Psychiatry and Biobehavioral Sciences; Director, UCLA Integrative Center for Neurogenetics, UCLA
(Neurogenetics Affinity Group & Consortium for Neuropsychiatric Phenomics Seminar)
4:00 pm – 5:00 pm, 159/173 Boyer Hall
Do Chaperones Need Chaperoning? Protein Homeostasis and Neurodegenerative Disease
Ron R. Kopito, Department of Biology, Stanford University School of Medicine, California
(Molecular Biology Institute Thursday Seminar)
FRIDAY, June 7, 2013
9:00 am – 10:00 am, Jolyon West Auditorium, C8-183 Semel Institute (formerly NPI)
Early Identification and Services for Autism Spectrum Disorder (ASD): Primary Care and Public Health Considerations
Alice Kuo, Associate Professor of Internal Medicine, Pediatrics & Health Services; Chief, UCLA Medicine-Pediatrics Section; Director, UCLA Combined Internal Medicine and Pediatrics Residency Program; UCLA CART Investigator and Director of Education & Training
(The UCLA Center for Autism Research and Treatment {CART}Affinity Group Lecture)
12:00 pm – 1:00 pm, Gonda First Floor Conference Room, 1357
Title to be Determined
Kimberly McDowell, Postdoctoral Fellow, Chesselet Laboratory, Department of Neurology, UCLA
(Training Program in Neural Repair Seminar)
MONDAY, June 10, 2013
11:00 am – 12:00 pm, Gonda 1st Floor Conference Room, 1357
Biomarker Studies for Male and Female Reproductive Health
Maris Laan, Professor, Institute of Molecular and Cell Biology, Biology and Geography, University of Tartu, Estonia
(Human Genetics Seminar)
3:00 pm – 4:00 pm, C-128 RNRC
Physical Therapy - Assessment and Treatment for Patients with Cognitive and Movement Disorders
Savina Kollmorgen, Bright Star Physical Therapy
(Alzheimer’s Disease Research Forum [ADRF])
TUESDAY, June 11, 2013
11:00 am – 12:00 pm, Jolyon West Auditorium, C8-183 Semel Institute (formerly NPI)
Plaque and Tangle Imaging in the Early Detection of Dementia
Linda Ercoli, Associate Professor, Division of Geriatric Psychology; Director, Geriatric Psychology Service; Director, Geriatric Psychology Postdoctoral Fellowship Training Program, Semel Institute, UCLA
(Semel Institute for Neuroscience & Human Behavior Grand Rounds)
4:00 pm – 5:00 pm, Neuroscience Research Building Auditorium
Joint Seminars in Neuroscience will resume Fall, 2013.
WEDNESDAY, June 12, 2013
9:00 am – 10:00 am, Neuroscience Research Building Auditorium, 132
Title and Speaker to be Determined
(Neurology Grand Rounds)
4:00 pm – 5:00 pm, Gonda First Floor Conference Room, 1357
Center for the Study of Parkinson’s Disease Colloquia will resume Fall, 2013.
THURSDAY, June 13, 2013
9:00 am – 5:00 pm, Neuroscience Research Building Auditorium, 132 Prion-Like Pathogenesis in Neurodegenerative Diseases
9:00 am Dave Teplow, UCLA; "Pontifications on prions, proteins, and pathology"
9:45 am Ron Wetzel, University of Pittsburgh; “The huntingtin exon-1 (mis)folding landscape: energetically plausible candidates for the HD toxic species”
10:30 am Coffee Break
10:45 am Susan Lindquist, Whitehead Institute for Biomedical Research; “Prion-like and non-prion-like protein folding problems: From yeast to neurons”
11:30 am General Discussion, facilitated by William Yang, UCLA
12:15 pm Lunch Break
1:30 pm Joel Buxbaum, Scripps Research Institute, “An unexpected natural ally in neurodegenerative disease: inhibiting aggregation in vivo and in vitro”
2:15 pm Virginia Lee, University of Pennsylvania; “Transmission of -synuclein in Parkinson’s disease”
3:00 pm Coffee Break
3:15 pm Ron Kopito, Stanford; “Prion-like cytoplasmic transfer of polyglutamine aggregates”
4:00 pm General Discussion, facilitated by Anne Messer, Wadsworth Center
(A Symposium Sponsored by the CHDI Foundation, the UCLA Department of Neurology, and the UCLA Brain Research Institute)
4:00 pm – 5:00 pm, 159/173 Boyer Hall
Molecular Biology Institute Thursday Seminars will resume Fall, 2013.
FRIDAY, June 14, 2013
12:00 pm – 1:00 pm, Gonda First Floor Conference Room, 1357
Training Program in Neural Repair Seminars will resume Fall, 2013.
TUESDAY, June 18, 2013
11:00 am – 12:00 pm, Jolyon West Auditorium, C8-183 Semel Institute (formerly NPI)
Title and Speaker to be Determined
(Semel Institute for Neuroscience & Human Behavior Grand Rounds)
WEDNESDAY, June 19, 2013
9:00 am – 10:00 am, Neuroscience Research Building Auditorium, 132
Title and Speaker to be Determined
(Neurology Grand Rounds)
THURSDAY, June 20, 2013
4:00 pm – 5:00 pm, Gonda 1st Floor Conference Room, 1357
Surface-Modified Proteinous Microspheres and Self-assembled Cyclic D, L-alpha-Peptides as Potential Therapeutics for Alzheimer’s Disease
Shai Rahimipour, Senior Lecturer, Department of Chemistry, Bar-Ilan University, Israel
(Special Lecture)
The Neuroscience Calendar will resume August 2013.
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